N-Acetyl Cysteine Reduces Cisplatin Ototoxicity
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چکیده
منابع مشابه
N-acetyl Cysteine N-acetyl Cysteine Inhibits Exercise-induced Lymphocyte Apoptotic Protein Alterations
PURPOSE: To investigate the effect of strenuous exercise and antioxidant administration on proand antiapoptotic protein expression in intestinal lymphocytes. METHODS: Female C57BL/6 mice (N = 52) were randomly assigned to receive N-acetyl cysteine (NAC; 1 g.kg(-1)) or saline (SAL) 30 min before treadmill exercise (EX) for 90 min and 2 degrees slope (30 min at 22 m.min(-1), 30 min at 25 m.min(-1...
متن کاملPreventing cisplatin induced ototoxicity by N-acetylcysteine and salicylate.
OBJECTIVES In this study we investigated if CP induced ototoxicity could be prevented or reduced by the use of salicylate and N-acetylcysteine. PATIENTS AND METHODS Fifty-four patients (28 females, 26 males; mean age 37+/-9.5 years; range 29 to 71 years) who had cisplatin chemotherapy due to solid organ tumors were enrolled in the study. The patients were randomized into three groups, with 18...
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n-acetyl cysteine (nac), as a nutritional supplement, is a greatly applied antioxidant in vivo and in vitro. nac is a precursor of l-cysteine that results in glutathione elevation biosynthesis. it acts directly as a scavenger of free radicals, especially oxygen radicals. nac is a powerful antioxidant. it is also recommended as a potential treatment option for different disorders resulted from g...
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laryngopharyngeal reflux (lpr) is a variant of gastroesophageal reflux disease (gerd) in which the stomach contents go up into the pharynx and then down into the larynx. lpr causes a wide spectrum of manifestations mainly related to the upper and the lower respiratory system such as laryngitis, asthma, chronic obstructive pulmonary disease, cough, hoarseness, postnasal drip disease, sinusitis, ...
متن کاملN Acetyl Cysteine, A novel Remedy for Poly Cystic Ovarian Syndrome
Background Poly cystic ovarian syndrome (PCOS) is the most prevalent endocrinopathy among women and the most common underlying diagnosis for anovulatory infertility. The role of insulin-resistance (IR) and hyperinsulinemia in pathophysiology and clinical manifestations of the syndrome depicts the importance of evaluation of the efficacy of insulin reducing medications. N acetyl cysteine (NAC) i...
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ژورنال
عنوان ژورنال: Erciyes Tıp Dergisi/Erciyes Medical Journal
سال: 2016
ISSN: 2149-2247,2149-2549
DOI: 10.5152/etd.2016.0068